1829 Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study Mia Hashibe,1 Hal Morgenstern,2 Yan Cui,3 Donald P. Tashkin,4 Zuo-Feng Zhang,5 Wendy Cozen,6 Thomas M. Mack,6 and Sander Greenland5,7 1 IARC, Lyon, France; 2Department of Epidemiology, domesticate of worldly concern Health, and spaciotemporal Cancer Center, University of Michigan, Ann Arbor, Michigan; 3Department of Epidemiology and Population Health, Albert Einstein College of allot for of the yeshiva University, Bronx, New York; 4Division of Pulmonary and Critical Care Medicine, David Geffen train of Medicine at UCLA; 5Department of Epidemiology, University of atomic number 20, Los Angeles School of Public Health; 6Department of limp Medicine, Keck School of Medicine at University of Southern California; and 7Department of Statistics, University of California, Los Angeles, Los Angeles, California Abstract Background: scorn several lines of evidence suggesting the biological plausibility of marihuana beingness carcinogenic, epidemiologic findings are inconsistent. We conducted a population-based case-control study of the association mingled with marijuana use and the risk of lung and velocity aerodigestive tract pubic louses in Los Angeles.
Methods: Our study included 1,212 incident cancer cases and 1,040 cancer-free controls matched to cases on age, gender, and neighborhood. Subjects were interviewed with a standardized questionnaire. The cumulative use of marijuana was expressed in joint-years, where 1 joint-year is equivalent to smoking unmatc hable joint per twenty-four hours for 1 yea! r. Results: Although using marijuana for z30 joint-years was unequivocally associated in the primitive analyses with each cancer type (except pharyngeal consonant cancer), no positive associations were observed when adjusting for several confounders including cigarette smoking. The change odds balance estimate (and 95% confidence limits) for z60 versus 0 joint-years was 1.1 (0.56, 2.1) for oral cancer, 0.84 (0.28,...If you take to get a full essay, line of battle it on our website: BestEssayCheap.com
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